Inhibitory effects of gabexate mesilate (FOY) on experimental DIC
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منابع مشابه
The effect of continuous arterial infusion of gabexate mesilate (FOY-007) on experimental acute pancreatitis.
The effectiveness of continuous arterial infusion of Gabexate Mesilate (FOY-007) on experimental acute pancreatitis was investigated. Acute necrotizing pancreatitis was induced by an injection of 10% Na-taurocholate (1ml/kg) into the main pancreatic duct of mongrel dogs. Animals were divided into three groups; Group A: non-treated control, Group B: after the induction of pancreatitis, injected ...
متن کاملProtective effect of gabexate mesilate (FOY) against pancreatic injuries induced by ethanol in rats.
Four-hour intravenous ethanol infusion at two doses of 0.5 and 1.0 g/kg.hr caused mild, but significant, rises in serum amylase and pancreatic water content as well as pancreatic histological changes such as interstitial edema in rats. These doses of ethanol also caused an impaired pancreatic adenylate energy charge levels and increased pancreatic mitochondrial fragility. The dose of 0.2 g/kg.h...
متن کاملEVALUATION OF INJECTABLE GENERIC DRUGS USING THERMOGRAVIMETRY AND THE INFLUENCE OF d-MANNOTOL ON THE STABLITLY OF GABEXATE MESILATE
Gabexate mesilate has been mainly used in the treatment of disseminated intravascular coagration (DIC) in Japan since 1983. Recently, several generic versions of injectable gabexate mesilate with or without d-mannitol as an additive have been put on the Japanese market. In our study, thermo gravimetry (TG) did not show any differences between gabexate mesilate products with or without d-mannito...
متن کاملEVALUATION OF INJECTABLE GENERIC DRUGS USING THERMOGRAVIMETRY AND THE INFLUENCE OF d-MANNITOL ON THE STABLITLY OF GABEXATE MESILATE
Gabexate mesilate has been mainly used in the treatment of disseminated intravascular coagration (DIC) in Japan since 1983. Recently, several generic versions of injectable gabexate mesilate with or without d-mannitol as an additive have been put on the Japanese market. In our study, thermo gravimetry (TG) did not show any differences between gabexate mesilate products with or without d-mannito...
متن کاملSusceptibility of Helicobacter pylori to simethicone and other non-antibiotic drugs.
The antifoaming agent simethicone (Lefax), the protease inhibitor gabexate mesilate (FOY), the antimycotic ketoconazole, and the hydroxyl scavangers dimethylsulphoxide (DMSO) and allopurinol were investigated for growth inhibition of Helicobacter pylori and representative strains of other bacterial species. H. pylori were selectively inhibited by 64-128 mg/L of simethicone, 64-128 mg/L gabexate...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1979
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.10.627